Muhsin Mahdi (1926-2007)

2 Lyases JASSEM G . MAHDI

Rania Al-Mahdi ́s thesis 25.10.15

The atypical MAP kinases ERK3 and ERK4 are activated by phosphorylation of a single serine residue lying within the signature sequence S-E-G in the activation loop. Thus far theregulation of ERK3 and ERK4 phosphorylation and thus activity is poorly understood. Herewe have screened mammalian dual-specificity MAP kinase phosphatases for their ability tointeract with ERK3 and ERK4 and ...

Irwin Rose (1926-2015).

On June 2, 2015, Irwin (Ernie) Rose died quietly in his sleep at age 88, after a long and fruitful lifetime of sleuthing for the secrets of life at the molecular level. Truly great scientists are much more than the sum of their publications and awards. This is especially true for Ernie who, when informed that he had been awarded the 2004 Nobel Prize in Chemistry, wondered aloud whether he reall...

David Hubel 1926–2013

Hydraulic microelectrode advancermade by David Hubel. David Hubel was a giant in our field, yet he waswarm, friendly, and humble in person. He and Torsten Wiesel, following in the footsteps of their mentor Steve Kuffler, discovered fundamental principles of information processing in the brain and fundamental principles of how the brain wires itself up. I think many people in the field see David...

Camillo Golgi (1843?1926)

Camillo Golgi studied the central nervous system [2] during the late nineteenth and early twentieth centuries in Italy, and he developed a staining technique to visualize brain cells. Called the black reaction, Golgi's staining technique enabled him to see the cellular structure of brain cells, called neurons, with much greater precision. Golgi also used the black reaction to identify structure...